If You’re Over 50, You Need to Add Urea to Your Skin Care
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If You’re Over 50, You Need to Add Urea to Your Skin Care

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β€œUrea is one of those unsung hero ingredients in dermatology,” says Austin, TX dermatologist Hallie McDonald. It’s naturally found in the skin’s barrier as part of the natural moisturizing factor (NMF), but levels decline with age, says Southlake, TX and Monroe, LA, dermatologist Janine Hopkins, MD. Dr. McDonald notes that this decline is part of the reason mature skin tends to feel drier, rougher and less elastic. To help remedy these changes, dermatologists recommend adding products with urea to your skin-care routine.

Featured experts

  • Janine Hopkins, MD is a dermatologist based inΒ  Southlake, TX and Monroe, LA
  • Dr. Sue Ellen Cox is a board-certified dermatologist in Chapel Hill, NC
  • Hallie McDonald, MD is a board-certified dermatologist in Austin, TX and the co-founder of ERLY

What makes urea a great ingredient for mature skin?

Mature skin tends to need both hydration and smoothing, says Dr. McDonald, and that’s where urea comes in. β€œFor aging skin that tends to become drier, thinner and more prone to rough texture, urea works two ways: it’s both a humectantβ€”drawing water into the skinβ€”and a gentle keratolytic, meaning it softens and smooths rough, flaky patches,” explains Dr. Hopkins. β€œThis dual action helps restore suppleness and reduce that crepey texture we often see in mature skin.”

The benefits of urea in skin care

β€œFor women over 50, I recommend daily hydration and gentle exfoliation with a body cream containing urea,” Chapel Hill, NC dermatologist Sue Ellen Cox, MD, previously told us. β€œUrea naturally attracts water and softens excess keratin in the outer skin layers, leading to soft, hydrated skin,” she explains.

β€œAt lower concentrations (around two to 10 percent), urea hydrates by attracting and holding water in the skin. At higher concentrations (10 to 20 percent), it helps smooth roughness by loosening the β€˜glue’ that binds dead skin cells together,” explains Dr. McDonald. β€œI often compare it to a good houseguestβ€”it doesn’t just bring extra water to the party, it tidies up while it’s there.”

Dr. Hopkins says urea can help smooth fine lines on the face caused by dryness, while in body care, it has the power to tackle dry, scaly areas on the body that don’t respond well to typical moisturizers. Urea is also soothing as it can help reduce itching and tightness that can accompany dryness with age, says Dr. Hopkins. Additionally, β€œby breaking down thickened skin, urea also helps other active ingredientsβ€”like peptides, retinoids or antioxidantsβ€”work more effectively.”

Dr. McDonald agrees adding that β€œFor patients already using serums with hydrating or firming ingredients, layering a urea cream on top can help those actives penetrate more effectively while giving the skin an extra drink of water.” Beyond mature skin, urea-based products are also especially great for anyone with keratosis pilaris or thick callused areas, she says.

Products with urea to try

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Both Dr. Hopkins and Dr. McDonald recommend the La Roche-Posay Lipikar line. Dr. Hopkins says this lotion, designed for dry skin, is one of her favorites. It contains urea, shea butter and allantoin, which help soften and smooth rough and bumpy skin.

La Roche-Posay Lipikar Urea 10% Roughness Smoothing Lotion

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Dr. Hopkins recommends this CeraVe cream that combines urea, salicylic acid and ceramides to help smooth rough skin.

CeraVe Moisturizing Cream with Salicylic Acid

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Eucerin is a great go-to brand when looking for urea-packed products. Dr. McDonald says this cream on the richer side is great for the face. If you’re looking for a body product from Eucerin, Dr. Hopkins says Eucerin Roughness Relief Lotion ($13) is an excellent option.

Eucerin UreaRepair Replenishing Face Cream

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Dr. McDonald says this lotion from ISDIN is great for treating flaky, dry skin or keratosis pilaris. It’s great to have on hand to promote healthier, younger-looking skin.

ISDIN Ureadin Ultra 10 Lotion



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