Paula’s Choice Niacinamide Serum: Read Real Reviews

If you’re dealing with enlarged pores, uneven tone or stubborn dark spots, there’s one serum that might be worth adding to your routine. In a recent survey of more than 400 NewBeauty readers,* a 49-year-old called out Paula’s Choice CLINICAL Niacinamide 20% Treatment ($55) for its visible impact, noting, “It shrinks my pores and takes care of dark spots.” 

The Formula

This highly concentrated formula features a first-of-its-kind 20-percent dose of niacinamide (vitamin B3), designed to penetrate the skin’s surface and dramatically improve the look of stretched pores, rough bumps and blotchy, red tone. It’s especially effective for those with oily, combination or sun-damaged skin, and works to fade post-blemish marks while restoring a smoother, more radiant complexion. 

The Reviews

Reviews from Paula’s Choice’s own site echo the praise. One user wrote, “Honestly this is the best niacinamide I have ever tried. It actually works! I noticed if I stop using this product, my skin looks very oily and dull. Then when I put it back on, the next day I’m oil-free and so much brighter.” Another shared, “Using this product made my skin the softest it has ever been,” noting a major improvement in texture and radiance. 

Another shared: “This is without a doubt the best product I’ve ever used. It has calmed my face so much. The redness is pretty much gone. My pores and skin texture are vastly improved as well. Please don’t ever discontinue this product. It’s the best.”

BUY ON DERMSTORE – $55

BUY ON SEPHORA – $55

Whether you’re targeting clogged pores, redness, dark spots or all of the above, this Paula’s Choice niacinamide serum is earning rave reviews for a reason.

*Source: BeautyEngine Advanced Research, 2025